Hola genes,

En ese tutorial indica los pasos en Apache como si fueras root, pero realmente no es necesario serlo para hacer las modificaciones que se piden.

Simplemente necesitas crear un archivo .htaccess con el contenido referido a tu usuario de Quijost. Por ejemplo asumiendo que tu usuario es genes, el archivo .htaccess podría ser:

WSGIDaemonProcess web2py user=genes group=genes \
                           display-name=GROUP}
WSGIProcessGroup web2py
WSGIScriptAlias / /home/genes/web2py/wsgihandler.py

<Directory /home/genes/web2py>
    AllowOverride None
    Order Allow,Deny
    Deny from all
    <Files wsgihandler.py>
      Allow from all
    </Files>
  </Directory>

  AliasMatch ^/([^/]+)/static/(.*) \
           /home/genes/web2py/applications/$1/static/$2
  <Directory /home/genes/web2py/applications/*/static/>
    Order Allow,Deny
    Allow from all
  </Directory>

  <Location /admin>
  Deny from all
  </Location>

  <LocationMatch ^/([^/]+)/appadmin>
  Deny from all
  </LocationMatch>


Ahora estuve haciendo mas pruebas y parece no tener modwsgi, porque estos son los errores que obtengo:

[Fri Apr 23 19:19:08 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIScriptAlias', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:19:08 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIScriptAlias', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:19:08 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIScriptAlias', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:19:08 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIScriptAlias', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:18:14 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIProcessGroup', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:18:14 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIProcessGroup', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:18:14 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIProcessGroup', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:18:14 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIProcessGroup', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:07:15 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIDaemonProcess', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:07:15 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIDaemonProcess', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:07:14 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIDaemonProcess', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:07:14 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIDaemonProcess', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:03:49 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIDaemonProcess', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:03:49 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIDaemonProcess', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:03:48 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIDaemonProcess', perhaps misspelled or defined by a module not included in the server configuration
[Fri Apr 23 19:03:48 2010] [alert] [client 201.213.107.72] /home/genes/public_html/.htaccess: Invalid command 'WSGIDaemonProcess', perhaps misspelled or defined by a module not included in the server configuration

Hola de nuevo genes, no me habia quedado muy conforme con la respuesta que te di, de que por culpa de cpanel no pudieramos actualizar y que tu usaras web2py. Asi que tras investigar mucho y hacer algunos trucos para solventar las dependencias de cpanel, python 2.6.5 esta instalado.
Python version: 2.6.5 (r265:79063, Apr 18 2010, 21:48:55)
[GCC 4.1.2 20080704 (Red Hat 4.1.2-46)]
Django version: (1, 2, 0, 'beta', 1)
MySqldb version: (1, 2, 3, 'gamma', 1)

He intentado hacer algunas pruebas de ver si funciona web2py, pero me da un error que en google no hay información para arreglarlo, asi que estoy atascado:
http://quijost.com/sandbox/web2py/

File "/home/quijost/public_html/sandbox/web2py/web2py_modpython.py", line 5, in handler
    req.subprocess_env['PATH_INFO'] = req.subprocess_env['SCRIPT_URI']

KeyError: 'SCRIPT_URI'

Si tienes alguna información de como arreglar el error, probablemente puedas hacer funcionar web2py.

Puede que funcione como comentas bajo modwsgi (no tengo mucha experiencia con mod_wgsi, así que tu dirás):

Estos son los archivos que he puesto:
.htaccess
RewriteEngine on
SetEnv PYTHON_EGG_CACHE /home/quijost
SetHandler python-program
PythonHandler web2py_modpython
PythonPath "sys.path + ['/usr/local/src/web2py'] + ['/usr/lib/python2.6/site-packages/']"
PythonDebug On

DirectoryIndex index.html

web2py_modpython.py
from mod_python import apache
import modpythonhandler

def handler(req):
    req.subprocess_env['PATH_INFO'] = req.subprocess_env['SCRIPT_URI']
    return modpythonhandler.handler(req)
default.py
def index():
    """ Main Index Page """
    age = 30
    name = "John Smith"
    return dict(name=name, age=age)

"""   
def index():
    page_info = DIV('Hello', ' ', 'World', _id='hellomsg', _class='info')
    return dict(page_info=page_info)
"""

index.html
{{extend 'layout.html'}} <!-- Contains your "master" layout //-->
 
<h2>Hello {{=name}}</h2>
 
<p>Your Age is {{=age}} years old, in about a year, you will be {{=(age + 1}} years old,
isn't that scary?</p>
 
{{if age < 21:}}
    <p>You are a kid!</p>
{{pass}}
 
{{extend 'layout.html'}} <!-- Contains your "master" layout //--> {{=page_info}}

Hola Miguel,

Este tema es viejo, casi de hace 3 años. Actualmente usamos Python 2.7 de base. La receta de webfaction no es aplicable ya que es para python 2.4 y usando mod_python.

Actualmente usamos mod_wsgi 3.4 por lo que directivas como PythonDebug On no son aplicables ya que son solo para mod_python (obsoleto).

Puedes usar la directiva:

DirectoryIndex index.py
Para ejecutar un archivo .py como wsgihandler.py. Tampoco hay necesidad de tener una instalación del propio web2py, porque este ya se encuentra instalado por defecto como paquete en los servidores de Quijost.